Invitro Bioanalytical Scientist

Job Title: Invitro Bioanalytical Scientist
Job Location: Hyderabad

About Syngene : Syngene (www.syngeneintl.com) is an innovation-led contract research, development
and manufacturing organization offering integrated scientific services from early discovery to commercial
supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has
placed safety at par with business performance with shared responsibility and accountability,
including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines
 Overall adherence to safe practices and procedures of oneself and the teams aligned
 Contributing to development of procedures, practices and systems that ensures safe operations
and compliance to company’s integrity & quality standards
 Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and
operational discipline at the workplace at all times.
 Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following
environment, health, and safety (EHS) requirements at all times in the workplace.
 Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are
completed on time by all members of the team including self
 Compliance to Syngene’ s quality standards at all times
 Hold self and their teams accountable for the achievement of safety goals
 Govern and Review safety metrics from time to time

Core Purpose of the Role :
 To participate in sample processing for PK, ADME assays and handling of LCMS/MS. Ability to adapt to
the dynamic team environment
 Processing of different matrices samples of PK studies
 Optimization of test compounds manually as well as automated on LCMS/MS
 Develop methods with the team lead
 Independently handling of HPLC for UV based samples analysis.
 Documenting the lab note books online and compound management

Role Accountabilities
Leadership Capabilities

Syngene Values
All employees will consistently demonstrate alignment with our core values
 Excellence
 Integrity
 Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)
 Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices
for the company and oversee compliance with those practices within Biologics business. Play an
active leadership role in monitoring and verifying safety performance through Gemba walks and
other safety-led activities.
 Foster a corporate culture that promotes an environment, occupational health, safety, and
sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
 Put people at the heart of our success by providing clear, active leadership defined by the Syngene
leadership framework setting high standards of people management, career planning and talent
retention as a priority.

Specific requirements for this role
1. Experience
2. Demonstrated Capability
3. Education

Experience
 Minimum 3-5 years of experience in handling ADME assays and HPLC and LCMS/MS
Skills and Capabilities
 Expertise in column selection, mobile phase selection, solvent preparations and sample processing
techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction is mandatory
 Sample processing of New chemical entities from various in-vitro and in-vivo studies executed in Preclinical
discovery by using appropriate extraction methods
 Should be able to develop and validate LC-MS based qualitative/quantitative methods and apply them in
routine analysis
 Should be well versed with internet-based literature search and capable of implementing the Learnings as
and when required
 Candidate is expected to have basic understanding in interpretation of Mass/UV Spectra
 Should ensure preventative maintenance and calibration schedules of HPLC & mass spec by coordinating
with vendor and support staff
 General understanding of Drug metabolism and Pharmacokinetics
 Should be able to deliver scientific presentation in departmental journal club and write official Project
reports

Education
 M. Pharm in Pharmaceutical sciences, Pharmaceutical Analysis who has interest and passion for LC/MS
related bioanalysis

Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.