Title:  Senior Principal Investigator

Job Description

Designation:  Group Lead

Job Location:  Hyderabad
Department:  Discovery Chemistry – Synthetic Chemistry

About Syngene:  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply. 

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit.

Mandatory expectation for all roles as per Syngene safety guidelines

•    Overall adherence to safe practices and procedures of oneself and the teams aligned

•    Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards

•    Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times. 

•    Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.

•    Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self

•    Compliance to Syngene’ s quality standards at all times

•    Hold self and their teams accountable for the achievement of safety goals 

•    Govern and Review safety metrics from time to time 

Role Requirements:

Ph.D. degree and or post-Doctoral research with a minimum of 6-10 years of CRO experience with excellent communication skills is preferred.

• The candidate should manage a team of 20-30 FTEs and capable of designing scheme, troubleshoot, problem solve independently, and execute high-profile project. The person should be flexible working shifts as per the organizational policy. The candidate should be excellent in cross functional teamwork and excellent in customer engagement.

Strategic Responsibilities

Safety:

• Commitment to safety (self, team, lab, and the organization) always
• Ensuring ZERO safety incidents in the lab/organization
• Ensuring ZERO safety non-compliances at workplace. 
• Reporting incidents (or near-misses) and learnings from those incidents to avoid recurrence
• Near miss reporting 1 per year per employee, Reduction in number of first aid injuries reported compared to previous FY, Review SOPs, and checklists for completeness of information related to safety

Quality:

• Ensure to comply with Syngene’ s quality standards and services (self and team) always
• ZERO data integrity incidents
• Adhere to the ALCOA+ principles in all data generated. Ensuring adherence to all Syngene policies related to data integrity by all team members.
• Maintain confidentiality
• Zero repeat audit observations, Zero major and critical observations in external audits, SOP’s vs Practices:
• Review and implement necessary refinements for continuous training, testing, and tracking SOP compliance
• Deviations <= 2% within the fiscal year, tracked monthly

Delivery

• Responsible for Project Health Index: Project planning, Execution, Deliverables including tracking of KPIs for his/her team and Quality of services (internal/client metrics)
• Achieve per-quarter improvement in key FY25 KPIs, per OU per plan, Achieve per-quarter improvement in key FY25 KPIs, per OU per plan, 18-20 steps per FTE per month, 6 compounds/FTE/month, 70% targets TAT within 30 days for deliverables <0.1 g scale and 5 CE/FTE/month for scales >0.1 g scale.
• Set up process, governance & tools for effective, transparent, and collaborative management of the projects in discussion with Group Leaders and Head of the department.

Engagement:

• Good in engaging with internal stakeholders (weekly reports, experimental for completed final compounds etc). Zero flaw in presentations and report, real time, and flawless communication
• 0% business attrition w.r.t scientific environment and work culture
• Excellent in team and cross-functional engagement
• The candidate should train junior TLs to bring to speed

Cost:

• Manage lifecycle of various lab infrastructure, instruments.
• Ensure optimum resource utilization and cost efficiency.

Compliance:

• Adhere to the ALCOA+ principles in all the experiments and data generated. Ensuring adherence to Syngene policies related to data integrity by all team members.
• ALCOA+ deviations <= 2% within the fiscal year, tracked monthly, zero data integrity incidents: Breaches that would lead to a material breach with client or regulator
• Gemba walk compliance at 100%, Timesheet compliance at 100%
• Confidentiality compliance
• Ensuring all assigned mandatory training related to data integrity, health, and safety measures are completed on time by all team members.

People:

• Leadership Next and Succession planning for critical roles – Reduce critical talent attrition by <5%, create succession plans for critical roles
• Build competencies and skills that are required to achieve current and future business needs.

Technical/functional Skills:

• The candidate should have excellent knowledge of modern synthetic methodology including asymmetric synthesis, heterocyclic chemistry, catalysis and the reaction mechanism is expected. 
• Should be expert in synthetic problem solving/troubleshooting skills.
• Excellent communication skills including face to face and virtual interactions with team and clients. Must have exceptional Presentation skills.
• The candidate should maintain an accurate scientific notebook, draft concise written reports for publications.

 Managerial Skills:

• Expertise in handling multiple collaborations.
• Demonstrated in handling a team size of 13-20 FTEs
• Worked effectively with interdisciplinary teams.
• Efficient Lab management skills
• The Leader must demonstrate the essential qualities of People Management.
  • Giving & receiving performance-enhancing feedback
  • Setting clear performance expectations
  • Conducting challenging performance conversations
  • Coaching individuals toward improved performance
  • Delegating tasks
  • Creating accountability
  • Lead the change

Syngene Values

All employees will consistently demonstrate alignment with our core values

•  Excellence
•  Integrity
•  Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

• Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
• Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.

• Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Specific requirements for this role

1. Experience
2. Demonstrated Capability
3. Education

Experience:

• 9 - 12 Years

Skills and Capabilities:

Technical/functional Skills:

• The candidate should have excellent knowledge of modern synthetic methodology including asymmetric synthesis, heterocyclic chemistry, catalysis and the reaction mechanism is expected.
• Should be expert in synthetic problem solving/troubleshooting skills.

• Excellent communication skills including face to face and virtual interactions with team and clients. Must have exceptional Presentation skills.
• The candidate should maintain an accurate scientific notebook, draft concise written reports for publications.

Education:

Phd + Post Doc

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.