Site Head

Job Title: Site Head

Job Location: Bengaluru

Reporting to: Head of CDMO Business

About Syngene :  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance to Syngene’ s quality standards at all times
• Hold self and their teams accountable for the achievement of safety goals
• Govern and Review safety metrics from time to time

Core Purpose of the Role: The Site Head – API Manufacturing is responsible for end-to-end leadership of a CDMO API manufacturing site, ensuring safe, compliant, cost-effective, and customer-centric operations. The role drives operational excellence, regulatory compliance, capacity utilization, profitability, and strong customer confidence while building a high-performance leadership team

Role Accountabilities:

1. Overall Site Leadership

• Provide full P&L ownership for the API manufacturing site.
• Lead cross-functional teams including Manufacturing, Quality (QA/QC), EHS, Engineering, SCM, MSAT, and Site Services.
• Build a strong safety, quality, and performance-driven culture.
• Act as the primary site representative to customers, regulators, and corporate leadership

2. Manufacturing & Operations Excellence

• Ensure consistent achievement of production targets across clinical, pilot, and commercial API campaigns.
• Drive capacity utilization, throughput improvement, and cycle-time reduction.
• Lead continuous improvement initiatives (Lean, Six Sigma, OPEX, TPM).
• Ensure robust planning, scheduling, and campaign management aligned with customer commitments.

3. Quality & Regulatory Compliance

• Ensure 100% compliance with global regulatory requirements (USFDA, EMA, PMDA, CDSCO, WHO, etc.).
• Own inspection readiness and successful outcomes for regulatory and customer audits.
• Drive strong data integrity, GMP discipline, deviation management, and CAPA effectiveness.
• Partner with Quality leadership to embed a "Right First Time" culture.

4. EHS & Sustainability

• Own site-level EHS performance with zero tolerance for safety incidents.
• Ensure compliance with environmental regulations and sustainability goals.
• Drive process safety, hazard analysis, waste minimization, and energy efficiency programs.

5. Customer Centricity & CDMO Delivery

• Serve as an executive sponsor for key CDMO customers.
• Ensure on-time, in-full (OTIF) delivery and high customer satisfaction.
• Support customer audits, technical discussions, and issue resolution.
• Collaborate with Business Development and Program Management for seamless project execution.

6. Financial & Cost Management

• Drive cost competitiveness through yield improvement, RM optimization, and fixed-cost absorption.
• Manage site budgets, capex planning, and cost control.
• Improve EBITDA and PAT through productivity and portfolio mix optimization.

7. Technology Transfer & Scale-up

• Oversee successful tech transfer from R&D to pilot and commercial manufacturing.
• Ensure robust scale-up, process validation, and lifecycle management.
• Partner with MSAT/R&D for process robustness and manufacturability.

8. Talent & Leadership Development

• Build and mentor a strong site leadership team.
• Drive succession planning and leadership development.
• Foster collaboration, accountability, and high employee engagement.

Syngene Values

All employees will consistently demonstrate alignment with our core values

• Excellence
• Integrity
• Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

• Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
• Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
• Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Qualifications & Experience

• PhD / M.Tech / M.Sc. / B.Tech in Chemical Engineering, Chemistry, or related discipline.
• 18–25+ years of experience in API manufacturing, with significant exposure to CDMO/CMO environments.
• Prior experience as Site Head / Plant Head / Manufacturing Head preferred.
• Strong exposure to global regulatory inspections.