Senior Research Scientist

JOB DESCRIPTION

Designation: Senior Research Scientist

Job Location: Bangalore

Department: Immunology

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose: We are looking for an experienced oncology/immuno-oncology scientist to drive pre-clinical drug discovery projects.

Key Responsibilities:

• For running independent project(s) in the areas of oncology/immuno-oncology
• For driving the assigned project with full commitment,
• To champion the biology of project, MoA, PK/PD correlation, models required to drive the project and work in collaboration with team members within the domain, across different domains and across department
• To take active participation in running experiments, compiling the data in required format and preparing study reports
• To train and mentor other scientists in a timely manner
• To work in a collaborative fashion with research scientists from various disciplines

Educational Qualification:Masters with Sound knowledge of oncology/immuno-oncology with focus on in vivo experience in handling multiple syngeneic and xenograft models.

Required Skills:

Scientific Execution & Study Leadership

• Design, plan, execute, and interpret in vivo pharmacology studies in oncology and immuno-oncology (efficacy, PK-PD, MOA).
• Demonstrate strong working knowledge of syngeneic and xenograft tumor models, including study setup, monitoring, and endpoint analysis.
• Perform and oversee key experimental procedures:
• Tumor cell implantation
• Compound dosing (multiple routes)
• Tumor measurement and monitoring
• Blood collection for PK
• Tissue collection for PD and downstream analysis
• Support mechanistic studies through integration of in vitro/ex vivo experiments as needed.
• Contribute to model development, optimization, and validation to enhance translational relevance.

Team Leadership & Collaboration

• Lead and mentor a small team (2–3 scientists/associates) in the in vivo pharmacology lab.
• Provide scientific and operational guidance, ensure quality execution, and review experimental data.
• Foster a collaborative, high-performance culture within the team and across cross-functional groups (biology, DMPK, biomarker, etc.).
• Coordinate study timelines, prioritize workload, and ensure timely delivery of project milestones.

Data Analysis & Communication

• Perform data analysis using GraphPad Prism (including appropriate statistical methods).
• Interpret results, generate clear conclusions, and provide actionable insights to project teams.
• Prepare and deliver high-quality data presentations to internal stakeholders and leadership teams.
• Ensure timely and transparent data sharing across platforms.

Laboratory Operations & Compliance

• Maintain accurate, complete, and timely electronic lab notebooks.
• Adhere to EHS, animal ethics, and regulatory compliance standards.
• Ensure best practices in experimental rigor, reproducibility, and data integrity.

Behavioral Skills: Good communication skills, good presentation skills, hardworking, sincere and a team player. Must demonstrate integrity and take accountability of their work

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.