Senior Research Investigator

JOB DESCRIPTION

Designation: Senior Research Investigator

Job Location: Bangalore

Department: Medicinal Chemistry – Drug Discovery

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Key Responsibilities/ Technical/functional Skills:

• Performs chemical experiments accurately; synthesizes, purifies, acquires and analyzes data efficiently and independently following best lab practices and HSE protocols.

• Develops and analyzes the feasibility of synthetic routes, based on published or in-house precedent, to targeted compounds in collaboration with other scientists.

• Well versed with modern synthetic chemistry methodologies, reaction mechanisms and other enabling technologies, and proactively shares this knowledge to address current synthetic challenges within the project team.

• Helps the team in the development of new routes that: increase the efficiency of synthesis, address scale up considerations, or open up new areas of a core structure to modification.

• Basic understanding of fundamentals of medicinal chemistry, SAR analysis and proposal of new analogs based on hypothesis

• Effective engagement with other functions such as CADD, biology and PCO etc. to enhance design ideas

• Laboratory skills should be honed to a level that routinely allows high productivity.

• Operates and maintains equipment and instruments with a high degree of technical proficiency.

• Documents results of experiments in their ELN in compliance with standard operating procedures. Experimental details should be captured in a fashion sufficient to facilitate reproducibility.

• Proficiently utilizes basic departmental software such as SciFinder, Reaxys etc. and data shared within the group

• Frequently updates supervisor with detailed communication of plans and results and subsequent follow-up.

• Presents experimental results and updates in chemistry team meetings including meetings with BMS, as situation merits.

• Shows leadership by example with respect to safety by ensuring that policies are adhered to, and that adequate risk assessment is conducted on planned reactions.

• Assumes key project responsibilities such as collation and preparation of patent application experimental.

• Mentor the work of less experienced chemists.   

• Demonstrate leadership in safety, departmental infrastructure and demonstrates lab/department citizenship.

• Exhibits BMS core behaviors

Educational Qualification: Ph. D in Organic Chemistry

Technical/functional Skills: (Maximum 4-6 Points)

• The candidate must possess a strong background in the theory and practice of classical and modern synthetic organic chemistry with a thorough understanding of modern synthetic methods and reaction mechanisms
• The candidate is expected to possess excellent problem-solving skills and should have a demonstrated ability to use critical analysis to develop creative and fundamentally sound solutions
• Candidate must have expertise in the purification and characterization of organic compounds using chromatography and spectroscopic techniques including NMR, MS and IR spectroscopy
• Good verbal and written communication skills and a desire to work in a collaborative team environment are required; In supervisory and/or project leader roles
• The candidate must demonstrate the ability to provide direction, feedback, and assistance to others in an effective manner.

Behavioral Skills:

• Good communication and analytical skills
• Enthusiasm to learn quickly with minimal training
• Should be meticulous at documentation and capable of multitasking
• Team player and able to adjust in a fast pace work environment

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.