Title:  BBRC - Senior Research Associate - Mass spectromet

Date:  29 Nov 2024
Job Location:  Bangalore
Pay Grade:  9-II
Year of Experience:  2 - 5 Years

JOB DESCRIPTION

 

Designation: Senior Research Associate (9-II)
Job Location: Bangalore
Department: Translational Medicine

 

About Syngene,
Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

 

Job Purpose (1-2 Lines): 
The candidate will be a part of translational medicine and perform routine mass analysis of mAbs and antigens using mass spectrometry. 

 

Key Responsibilities: Must have technical skills

1.    Experience in mass spectrometry, focusing on the analysis of monoclonal antibodies (mAbs) and antigens
2.    Proficiency in protein purification techniques, specifically using AKTA Pure and AKTA systems for affinity, ion-exchange, and size-exclusion chromatography.
3.    Proficiency in protein identification using database searches (e.g., UniProt) with a foundational knowledge of bioinformatics applications to support mass spectrometry-based protein characterization.
4.    Accountability for conducting precise and reproducible experiments, ensuring high-quality data and troubleshooting as needed.
5.    Strong documentation skills, with experience in detailed lab notebook maintenance and thorough data recording to support data management and integrity.

 

Educational Qualification: M.Sc/ M.Tech/ M.Pharm or similar qualifications in Biochemistry/ Biotechnology/ Cell Biology/ Biomedical Sciences/ Life Sciences 

 

Must have technical skills
1. Experience in mass spectrometry, focusing on the analysis of monoclonal antibodies (mAbs) and antigens
2. Proficiency in protein purification techniques, specifically using AKTA Pure and AKTA systems for affinity, ion-exchange, and size-exclusion chromatography.
3. Proficiency in protein identification using database searches (e.g., UniProt) with a foundational knowledge of bioinformatics applications to support mass spectrometry-based protein characterization.
4. Accountability for conducting precise and reproducible experiments, ensuring high-quality data and troubleshooting as needed.
5. Strong documentation skills, with experience in detailed lab notebook maintenance and thorough data recording to support data management and integrity.

 

Desirable technical skills:

1. Expertise in peptide mapping, deglycosylation, and post-translational modification (PTM) analysis.
2. Relevant experience in the biotechnology industry.
3. Hands-on experience in protein expression within mammalian cell lines, including HEK, CHO, and Sf9.
 

Experience: 2-3 years of relevant work experience

 

Behavioral Skills: Must have behavioral Skills    

1. Ability to prioritize tasks and manage multiple projects simultaneously in a dynamic, fast-paced environment with evolving requirements.
2. Quick learner with a strong ability to collaborate effectively with team members.
3. Strong oral, written, and presentation skills to facilitate effective communication within a multi-disciplinary team.
 

Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.