Title:  Research Scientist (ADME)

Date:  10 Jul 2024
Job Location:  Bangalore
Pay Grade:  7-I
Year of Experience:  9 - 12 Years

Designation: Research Scientist

Job Location: Bangalore


About Syngene:

Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.


At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit.


The mandatory expectation for all roles as per Syngene safety guidelines:

  • Overall adherence to safe practices and procedures of oneself and the teams aligned
  • Contributing to the development of procedures, practices and systems that ensures safe operations and compliance to companys integrity & quality standards
  • Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
  • Ensuring safety of self, teams, and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
  • Ensure all assigned mandatory training related to data integrity, health, and safety measures are completed on time by all members of the team including self
  • Compliance with Syngene's quality standards at all times.


Job Purpose:

A highly motivated individual with a strong interest in In-vitro ADME assays to lead and support Amgen’s drug discovery projects by providing scientific oversight and managing people while monitoring team performance

Key Responsibilities:

  • Plan activities to screen compounds in In-Vitro metabolism, protein binding, transporters, permeability assays to support drug discovery projects
  • Design and execute investigative and mechanistic assays to address the issues and support the discovery programs
  • Plan and monitor the weekly in-vitro studies by the project requirements and communicate the data to the internal and external stakeholders
  • Diligent data review, preparing presentations, and presenting to the client.  
  • Ensure the team captures raw data, metadata, and processed data in Logbooks, LNB/eLNs
  • Attention to detail and effective communication and documentation skills is desired.
  • Forecast and maintain the critical inventories to maintain smooth workflows.
  • Maintain 100% compliance with safety, integrity and QA policies.
  • Adherence to Good Research practices of the organization.

Syngene Values:

All employees will consistently demonstrate alignment with our core values.

  •  Excellence
  •  Integrity
  •  Professionalism

Educational Qualification: M.Sc (Chemistry/Biological Sciences)/M. Pharm from a reputed University

Work Experience: 9 to 12 years of experience in industry.

Technical/Functional Skills:

  • Excellent understanding of drug discovery concepts.
  • Sound knowledge in DMPK, In vitro ADME, in vivo PK/ADME studies, bioanalytical, metabolite identification, and profiling, etc.
  • Experience with both small and large molecules, biochemical and cellular assays, multiple technological platforms, automation, and high-throughput screening
  • Strong background in automation, with a track record of working with small molecule drug discovery programs
  • Experience with liquid handling platforms is a plus

Behavioral/Managerial Skills:

  • High interpersonal skills, and excellent oral & written communication skills.
  • Problem-solving, time-management skills, multi-tasking.
  • Excellent organizational skills, strong time management and process-oriented thinking
  • Experience in data management, inventory creation and integration of the hardware with software
  • Teamwork with internal stakeholders- chemists, biologists, and external partners to implement processes and tools that will foster the science
  • Ensure the development of effective environment, health, and safety (EHS) practices for the company and oversee compliance with those practices

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.