Title:  Protein Purification Scientist

Job Title: Protein Purification Scientist

Job Location: Bangalore

About Syngene:

Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply. 

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned.
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards.
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace always.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements always in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self.
• Compliance to Syngene’s quality standards at all times.

Core Purpose of the Role:  We are seeking a skilled and enthusiastic Protein biochemist/protein purification scientist to join the protein purification group in the protein tech - SARC Biology, a multidisciplinary team with capabilities in molecular cloning, expression and purification of proteins, including antibodies, bi-specifics and microbially expressed proteins. The ideal candidate will have broad laboratory training, deep scientific curiosity and a positive approach to work in a team-based research environment along with a track record of creative problem-solving and enthusiasm for taking on difficult research challenges.

Role Accountabilities:

• Comprehensive theoretical and practical knowledge and experience in mammalian and microbial (desirable) recombinant protein purification techniques (including affinity, ion exchange, HIC, SEC, CHT and reverse phase chromatography, TFF) and method development. Candidates having demonstrated hands-on experience in both mammalian and microbial projects will be preferred.
• Should have experience in analytical biochemistry (SEC-HPLC, SDS PAGE, Western Blot, Protein quantification, etc.)
• Strong FPLC/liquid chromatography experience – ability to program, operate, and troubleshoot purification equipment and experiments at small/pilot scale using the Cytiva AKTA platform including AKTA PURE, Explorer.
• Ability to learn new techniques, perform multiple tasks simultaneously, update technical data and maintain accurate records contemporaneously, follow instructions, and comply with company policies.
• Work according to established Standard Operating Procedure (SOP) and regulatory guidance.
• Should have excellent oral, presentation and written communication skills: Team player and customer-focused
• Should have good publication record.

Syngene Values: All employees will consistently demonstrate alignment with our core values

• Excellence
• Integrity
• Professionalism

Desired Technical Qualifications:  

• Demonstrated experience in optimizing purification of recombinant proteins from mammalian as well as microbial source.
• Knowledge and experience in packing resins in columns like XK, HiScale and BPG.
• Knowledge in moderate throughput purification techniques (e.g-Magbeads, Coupled Columns) is desirable
• Experience in bacterial and mammalian expression and molecular biology techniques will be an additional advantage.

Behavioral Skills:

• Able to work follow instructions and perform the tasks under the supervision of the project leader
• Fair interpersonal skills

Experience: 3 to 6 years of relevant experience.

Educational Qualification:  Master’s (M.Sc./M. Tech.) in biotechnology, biochemistry, structural biology, biophysics, bio-analytical chemistry or similar scientific fields.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.