Title:  Project leader

Date:  9 Jul 2024
Job Location:  Bangalore
Pay Grade:  6-I
Year of Experience:  6 - 9 Years

Syngene International:

Syngene International is an innovation-focused global discovery, development, and manufacturing organization providing integrated scientific services to pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries around the world. Syngene’s client include market leaders such as Bristol-Myers Squibb, Baxter, Amgen, GlaxoSmithKline, Merck KGaA and Herbalife. Syngene’s innovative culture is driven by the passion of its 5000 scientists who collaborate with clients across the globe to tackle technical challenges, augment R&D productivity, accelerate time to market, and lower innovation costs.


As part of Syngene’s ongoing expansion, we are launching a new scientific endeavor focused on delivering industry leading integrated therapeutic discovery and preclinical development on behalf of our global clients.  This new segment of our organization will feature an unwavering focus on creating novel therapeutics that improve the lives of people suffering from various diseases.  Creativity and innovation as well as a genuine spirit of collaboration is essential to the success of this endeavor.



Job Purpose:

The purpose of the role is to lead an Integrated Drug Discovery Project as a project leader


Key Responsibilities:

•            Provide strategic and scientific leadership to integrated drug discovery projects for our clients

•            Liaise with the Functional Head - Medicinal Chemistry on projects priorities and ensure that project deliverables are met.

•            As program leader supervise one/ three medicinal chemistry project(s).

•            Analyze SAR and design new set of compounds using CompChem tools to address various MedChem issues.

•            Provide regular updates on project progress to the Section Head - medicinal chemistry / Functional Leads and clients.

•            Work collaboratively with the CADD scientists, biologists, DMPK scientists and the safety pharmacologists.

•            Exceptional creativity and innovation in the genuine spirit of collaboration

•            Core commitment to safety, integrity, compliance, quality, and service



Educational Qualification:

•            Ph.D in organic chemistry / Medicinal chemistry from reputed universities in India / abroad. PDF in Medicinal chemistry/organic chemistry



Technical Skills and Experiences

•            Candidate should have a minimum of 2 - 8 yrs. experience in drug discovery from pharmaceutical or biotech industry.

•            Excellent understanding of the concepts of drug discovery, preferably having prior experience of progressing a project from hit identification to lead optimization.

•            Has prior experience working with a cross-functional team, comprising assay biologists, Structural biologists, DMPK scientists, computational chemists, and safety pharmacologists.

•            Familiarity with molecular modelling concepts and tools is desirable.

•            Strong knowledge of data analysis (SAR/SPR) and informatics tools.

•            Familiarity with cGMP and regulatory knowledge.

•            Strong Client communication and presentation skills.

•            Extensive knowledge and experience in synthesis planning, synthetic methods, and use of modern chromatographic and analytical tools.





Behavioral / Managerial skills:

•            Proven ability to lead and motivate the teams. 

•            Excellent written and verbal communication skills.

•            A team player / works well in multi-discipline teams

•            Builds strong plans to provide clarity for others, and utilizes time management tools and capabilities



Equal Opportunity Employer

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.