Principal Scientist - Translational Sciences

JOB DESCRIPTION

Job Title: Principal Scientist - Translational Sciences

Job Location: Bangalore

Department : Translational and Clinical Research

About Syngene :  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific  services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

 Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance to Syngene’ s quality standards at all times

Core Purpose of the Role :

To lead and execute clinical biomarker studies involving flow cytometry, next-generation sequencing (NGS), and related translational research platforms in a GLP/GCLP‑compliant environment.

Role Accountabilities

·  Lead end-to-end biomarker study execution under GLP/GCLP, including study planning, assay development, validation, sample analysis, data interpretation, and reporting.

·  Develop, optimize, and troubleshoot flow cytometry panels (immunophenotyping, receptor occupancy assays) and NGS workflows (RNA‑seq, targeted sequencing).

·  Ensure full compliance with established SOPs, regulatory guidance and data integrity requirements.

·  Collaborate with Quality Control and Quality Assurance for study review, deviation management, and audit readiness.

·  Prepare technical documents including protocols, method development reports, validation documents, and final study reports.

·  Contribute to scientific discussions, data reviews, project meetings, and client communications.

·  Mentor junior scientists on biomarker assays, instrumentation, troubleshooting, and compliance best practices.

Syngene Values

All employees will consistently demonstrate alignment with our core values

•  Excellence
•  Integrity
•  Professionalism

Specific requirements for this role

1. Experience
2. Demonstrated Capability
3. Education

Experience 

• Mid senior level experience in clinical biomarker assays within CRO, clinical research, or translational sciences environments.
• Hands-on expertise in clinical flow cytometry, NGS library preparation and sequencing workflows
• Proficiency with additional assay platforms such as qPCR, IHC and ELISA is highly desirable
• Experience working in GLP/GCLP and other regulatory‑driven laboratory environments.

Skills and Capabilities

• Advanced technical expertise in clinical flow cytometry including receptor occupancy assays
• Technical expertise in RNA isolation, QC and library preparation for NGS studies
• Strong problem-solving skills and scientific rigor.
• Excellent organizational skills and ability to manage multiple studies.
• Effective communication and interpersonal skills.
• Demonstrated ability to work under time-sensitive conditions.

Education 

Master’s in molecular Biology, biotechnology or translational sciences 

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.