Principal Scientist-CADD

JOB DESCRIPTION

Job Title: Principal Scientist

Job Location: Bangalore

Department: Computational & Data Sciences

About Syngene:  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific  services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance to Syngene’ s quality standards at all times
• Hold self and their teams accountable for the achievement of safety goals
• Govern and Review safety metrics from time to time

Core Purpose of the Role:

• Lead the implementation and successful completion of internal and client-oriented projects.
• Develop project proposals tailored to specific client requirements.
• Contribute technical expertise to organizational initiatives and collaborate with cross-functional teams.
• Guide and mentor team members while defining strategic roadmaps to strengthen and expand current capabilities.

Role Accountabilities

• Ensure timely delivery of assigned CADD projects by adhering to established quality standards and compliance with related SOPs.
• Responsible for applying computational, data-driven approaches to support drug discovery and development.
• Deep understanding of molecular modeling techniques for the design and evaluation of both small molecules and biologics.
• This position demands strong expertise in cheminformatics, including managing chemical data, developing and integrating tools to streamline research workflows, and leveraging machine learning for compound property prediction and lead optimization.
• Proficiency in programming languages such as Python, R, or Java, along with hands-on experience using cheminformatics tools & linux is essential.
• Identify and resolve problems where computational modeling can significantly improve the drug discovery process fostering a collaborative, team-oriented approach.
• Adherence to quality and project guidelines as per QA metrics, w.r.t. content accuracy, concise reporting, plagiarism, redundancy, relevance, formatting (spelling, grammar, typos).
• Maintain documentation for processes followed as per ALCOA+ principles.
• Attend and complete all mandatory trainings on time and maintain training records.

Leadership Capabilities

• Set the goals, define priorities, manage individual / team performance, organize people and activities to achieve goals.
• Mentor and develop a team, providing coaching, opportunities to develop skills, constructive and timely feedback on performance/progress toward goals/expectations.

Syngene Values

All employees will consistently demonstrate alignment with our core values

•  Excellence
•  Integrity
•  Professionalism

Specific requirements for this role

Education & experience: PhD / post-doc in Cheminformatics, Computational Chemistry, Bioinformatics, or related field.

Skills and Capabilities: Strong scientific expertise in Cheminformatics, molecular modeling and related disciplines, with demonstrated ability to interpret the results to provide rationale to drug discovery projects. Proficiency in drug discovery principles, with analytical thinking, scientific writing, and communication skills to deliver high-quality reports.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.