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Principal Scientist-Assay Biology

Date:  1 Sept 2026
Location: 

Bangalore, KA, IN, 560099

Division:  Discovery Services

 

JOB DESCRIPTION

 

Job Title: Principal Scientist – Assay Biology

Job Location: Bangalore

 

About Syngene:  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific  services from early discovery to commercial supply.

 

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

 

Mandatory expectation for all roles as per Syngene safety guidelines

 

  • Overall adherence to safe practices and procedures of oneself and the teams aligned
  • Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
  • Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
  • Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
  • Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
  • Compliance to Syngene’ s quality standards at all times
  • Hold self and their teams accountable for the achievement of safety goals

 

 

 

 

 

Core Purpose of the Role:

Senior Scientist to support in vitro research activities that are critical to Bicara project.

 

Key Roles and Responsibilities:

        1. Cell based Assays & Functional Studies
  • Conduct studies to assess anti-tumor activity across various tumor cell lines and indications.
  • Execute and optimize 2D and 3D co culture experiments incorporating PBMCs, stromal cells, and other relevant cell types.

 

  • Independently plan and perform a diverse portfolio of assays including:

 

        1. Flow cytometry
        2. Cell proliferation and inhibition assays
  2. Cytokine & Biomarker Profiling
        1. Luminex
        2. ELISA
        3. Cytometric Bead Array (CBA)
  3. Imaging & Kinetic Assays: Utilize and optimize Incucyte based real time imaging to monitor cell proliferation, apoptosis, cytotoxicity, and cell cell interactions.

 

  1. Data Analysis and Documentation
  1. Analyze large experimental datasets using standard software tools and prepare study summaries for internal reviews and cross-functional meetings.
  2. Maintain rigorous, timely, and compliant documentation in Electronic Lab Notebooks (ELNs).

5. Compliance & Data Integrity

  • Ensure adherence to organizational safety, quality, and EHSS standards.
  • Follow ALCOA+ principles and maintain accurate electronic lab notebook (ELN) records.
  1. Laboratory Operations
        1. Support routine lab activities including mammalian cell culture.
        2. Reagent preparation and aliquoting
        3. Logging and tracking of appropriate storage and inventory of critical reagents

Specific requirements for this role:

Education

  • Master’s degree (M.Sc.) or PhD in:
    • Biology / Biotechnology
    • Immunology / Cell Biology
    • Cancer Biology or related life sciences field

Experience

  • Scientist: 7-8 years of relevant industry experience post MSc. or 2years post PhD.
  • Hands-on experience (preferred) in:
    • Cell-based assays (proliferation, cytotoxicity)
    • Mammalian cell culture
    • Immunoassays (ELISA, Luminex, CBA)
    • Flow cytometry
  • Experience with data analysis tools (e.g., PLA, SoftMax Pro, GraphPad Prism, Excel)

 

Core Competencies

  • Strong interpersonal, analytical, presentation, and communication skills.
  • Ability to work effectively under tight timelines in a collaborative environment.

 

Syngene Values:

All employees will consistently demonstrate alignment with our core values

  •  Excellence
  •  Integrity
  •  Professionalism

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.

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