Principal Investigator
Bangalore, KA, IN, 560099
Designation: Principal Investigator - 6-I
Job Location: Bangalore
Department: CDAS-Chemical Development and API Supplies
About Syngene
Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.
Job Purpose (1-2 Lines)
Looking for a synthetic organic chemist (PhD in Organic chemistry) who will be able to lead a team addressing synthetic challenges and supporting scaleup activities in process research and development group. Previous experience of leading a team of scientists is essential.
Key Responsibilities:
The candidate should be able to lead a team of scientists with responsibilities towards development of safe and robust chemical processes for the preparation of intermediates/API in support of drug development activities.
Development work includes:
• Route scouting/proposal of alternate routes
• Providing insights and innovative solutions to project team members in order to address process related challenges.
• Candidate should communicate effectively with his own team members as well as with multiple teams like process engineering, process safety, analytical etc.
• Communicating & documenting development on the project through regular updates with concerned stakeholders.
Educational Qualification:
Candidate with PhD degree from a reputed institute/university with minimum post-doctoral experience of 2 to 3 years.
Technical/functional Skills:
Essential:
• Good understanding of organic chemistry fundamentals and reaction mechanisms.
• Previous experience in Pharmaceutical Process R&D demonstrating
o Coordination with multi-disciplinary teams of process R and D, process safety/engineering, pilot plant, quality control.
o Good understanding of analytical data generated from NMR, HPLC, GC etc.
• Publications in reputed international journals.
Preferable:
• Expertise in below mentioned areas
o Antibody-Drug Conjugates (ADC)
o Peptides
o Oligomers / Oligonucleotide chemistry
• Good understanding about cGMP facility in pilot plant and interaction with and quality assurance personnel
Experience:
5 to 9 years of total research experience (post-doctoral research and industry).
Behavioral Skills:
• Should be a good team player within and across cross functional teams.
• Should be self-motivated, creative and independent thinking individual.
• Should be a good mentor to junior members of the team he is a part of.
Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.