Invitro ADME Scientist

Job Title: Invitro ADME Scientist

Job Location: Bangalore/Hyderabad

Department: Discovery Biology

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose

• Highly lab-based role, conducting metabolism, Phys-Chem, Caco-2, LLC-PK1-MDR1, MDCK-II-MDR1, MDCK-II BCRP transporter assays in 24 well/ 96 well plate trans well assays using different matrices with highest quality

Key Responsibilities:

• Design and execute Caco-2, LLC-PK1-MDR1, MDCK-II-MDR1, MDCK-II BCRP transporter assays in 24 well/ 96 well/384 well plate trans well assays
• Able to handle Metabolism and Phys-Chem studies
• Reporting of executed studies without mistakes
• Raw data compilation, Report preparation, eLN updation on time.
• Presenting the study results clearly in the cross functional scientific meetings.
• Follow environment, health, and safety (EHS) requirements at all times in the workplace-ensuring individual and lab/plant safety.
• Ensure environment, health, and safety (EHS) measures are imparted via training and adhered within the team.

Educational Qualification:  

• M Pharm. in any pharmaceutical science or M Sc. in biological science.

Technical/functional Skills:

• Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assays
• Experience in conducting cell-based assays using wild type and transporter transfected cell lines
• Good, demonstrated knowledge in software such as Microsoft excel and Graph pad prism
• Report preparation and review of the reports ready to share with the clients
• Understanding the functionality, operation and maintenance of the instruments (TEER inst, Microscope, biosafety cabinet, LN2, etc.)

Experience:

• M Pharm. in pharmaceutical sciences or M SC in biological science with one to four years of Industrial experience in DMPK/ADME research.

Behavioral Skills:

• Demonstrate ability to be a team player.
• Commitment to deliver the study reports within the agreed timelines
• Adaptability to changes in the dynamic lab environment
• Communicate confidently with colleagues and collaborators in the meetings and presentation of study reports and evidence of publications in the PEER reviewed Journals

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.