In vivo Pharmacologist

Job Title: Invivo Pharmacology Scientist

Job Location: Bangalore

About Syngene:  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific  services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance to Syngene’ s quality standards at all times
• Hold self and their teams accountable for the achievement of safety goals
• Govern and Review safety metrics from time to time

Core Purpose of the Role:

The individual must possess excellent technical knowledge and experience in ‘animal models of Neuropathic pain combined with thorough understanding of delivery of in-vivo Pharmacology projects in these therapeutic areas. The individual should possess the ability to lead and influence matrix cross-functional teams with internal and external stakeholders to ensure projects are delivered on time and quality

Role Accountabilities

• Responsible to conduct assigned research projects including experiments with utilizing current concepts and recognized standard techniques.
• Responsible to set up the experimental designs, analysis of data and concluding from the progress.
• Record laboratory observations information in lab notebooks, database and document the experimental designs.
• Responsible for data analysis, perform calculations for the result of the experiment.
• Summarize the research and communicate result of research to the supervisor and client

Leadership Capabilities

• Adequate leadership skills & ability to influence and work with matrix cross-functional teams with internal and external stakeholders to ensure projects are delivered on time, and quality
• Ability to handle multiple concurrent tasks and changing priorities
• Attention to detail and ability to work independently.
• Good communication skills – verbal and written; Ability to plan, execute and keep experimental records & prepare protocols as needed; Mentor junior scientists; Demonstrate the ability to work in a collaborative environment
• Adhere all procedures related to data integrity, ensure documentation in compliance with ALCOA plus principles.
• Adherence to environment, health, and safety (EHS) requirements, Implementation of Safety and productivity improvement processes.

Syngene Values

All employees will consistently demonstrate alignment with our core values

•  Excellence
•  Integrity
•  Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

• Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
• Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.

• Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Specific requirements for this role

1. Experience: 3 - 6 years
2. Demonstrated Capability: Thorough understanding and practical hands-on experience on Animal models of pain and arthritis
3. Education: Master’s in Pharmacology/M.V.Sc Pharmacology 

Skills and Capabilities

• Hands-on experience in execution of pain models which includes Chemically Induced Nociception - Acetic acid induced writhing, Formalin induced tonic pain, Neuropathic Pain - Partial sciatic nerve ligation (PSNL), chronic constriction injury (CCI), Spinal Nerve Ligation (SNL) and Inflammatory Pain - Adjuvant (CFA) induced pain.
• Hands-on experience in handling acute inflammation models such as – LPS induced pulmonary inflammation; Carrageenan induced paw edema and Cytokine Induced Inflammation and peritonitis animal models.
• Hands-on experience in handling chronic inflammation models such as – Carrageenan Airpouch inflammation, Cotton Pellet Induced Granuloma and Bleomycin Induced Pulmonary Fibrosis.
• Will work independently or in association with senior scientists and other associates in the design and execution of in-vivo efficacy experiments in the relevant therapeutic area.
• Experience in animals handling (rodents and non rodents) such as dosing by various routes, bleeding by various routes, injections by various routes and surgical modalities which includes cannulation etc…
• Associate to provide technical, analysis and reporting outcomes of research for projects in relevant therapeutic area.
• Organizational skills and the ability to work in a highly collaborative environment are required.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.