Assay Biologist

Designation: Assay Biologist

Job Location: Bangalore

About Syngene:  Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance to Syngene’ s quality standards at all times
• Hold self and their teams accountable for the achievement of safety goals
• Govern and Review safety metrics from time to time

Position Summary

We are seeking a highly motivated and detail‑oriented Scientist to join our preclinical research team focused on oncology drug discovery and development. The successful candidate will contribute to in vitro studies supporting mechanism‑of‑action, efficacy evaluation, and translational research across a range of tumor cell lines and therapeutic modalities.

This role is ideal for individuals passionate about experimental biology, assay development, and generating high‑quality data to advance drug development programs.

Key Responsibilities

1. Cell‑based Assays & Functional Studies

• Conduct in vitro studies to assess drug efficacy, viability, cytotoxicity, and proliferation across multiple tumor cell lines.
• Design and execute advanced 2D and 3D co‑culture experiments incorporating PBMCs, CAFs, and other relevant cell types.
• Immunophenotyping by flow cytometry.
• Cytokine Profiling using Luminex, ELISA and CBA.
• Utilize and optimize Incucyte‑based real‑time imaging to monitor cell proliferation, apoptosis, cytotoxicity, and cell‑cell interactions.
• Proficiency in data analysis using tools such as Excel, GraphPad Prism, FlowJo, or equivalent.

2. Data Analysis & Documentation

• Analyze experimental datasets using standard software tools and prepare study summaries for internal reviews and cross-functional meetings.
• Maintain rigorous, timely, and compliant documentation in Electronic Lab Notebooks (ELNs).

3. Laboratory Operations

• Support general cell culture workflows, including routine maintenance of cell lines, mycoplasma testing and reagent preparation
• Manage laboratory inventory, track consumables, and assist with procurement processes to ensure smooth lab operations.

4. Core Competencies

• Strong analytical and problem‑solving skills.
• Excellent interpersonal communication and scientific writing abilities.
• Ability to work collaboratively in a fast‑paced, cross‑functional research environment.

Educational and Experience: 

• PhD in Life sciences or related field with hands on experience in assay development

Behavioral Skills:

• Good oral, written communication and presentation skills to work in a multi-disciplinary team.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.